Autopsy Results Reveal Ketamine as the Contributing Factor in the Passing of ‘F.R.I.E.N.D.S’ Star Matthew Perry in 2023.

The Tragic Passing of Matthew Perry: Autopsy Reveals Ketamine as Cause of Death.

Ketamine autospy
Source: Getty images

Autopsy Report Unravels Matthew Perry’s Cause of Death

The Los Angeles County Medical Examiner’s Office has unveiled the cause of death of beloved ‘F.R.I.E.N.D.S’ star Matthew Perry, who passed away in October. The autopsy report points to the acute effects of ketamine as the primary cause, accompanied by contributing factors such as drowning, coronary artery disease, and the influence of buprenorphine.

Perry’s Untimely Demise: Tragic Discovery in the Hot Tub

Matthew Perry, a cherished ‘F.R.I.E.N.D.S’ alum, was discovered unresponsive in his hot tub on October 28. The initial investigation revealed no signs of fatal injury or foul play. However, the subsequent autopsy report has shed light on the complex set of circumstances surrounding his untimely demise at the age of 54.

Ketamine Infusion Therapy: A Bid to Combat Depression and Anxiety

The autopsy report delves into Perry’s medical history, highlighting a previous diagnosis of diabetes, chronic obstructive pulmonary disease/emphysema, and a history of past drug use. Despite a period of 19 months of sobriety, Perry was undergoing ketamine infusion therapy for depression and anxiety. The last session occurred one and a half weeks before his tragic passing.

Ketamine Levels and Fatal Effects: Unraveling the Autopsy Findings

Despite engaging in therapeutic ketamine infusion therapy, the autopsy revealed unexpectedly high levels of ketamine (3,540 nanograms per milliliter) in Perry’s system. These elevated levels can lead to fatal effects, including cardiovascular overstimulation and respiratory depression. The report also noted drowning and coronary artery disease as contributing factors to his death.

Buprenorphine’s Influence: Additive Respiratory Effects

Buprenorphine, present in therapeutic levels, was identified as a contributing factor due to its “additive respiratory effects” when combined with the high levels of ketamine. This revelation adds complexity to the circumstances surrounding Perry’s passing, raising questions about the interaction of these substances within his system.

Understanding Ketamine: Medical and Recreational Applications

Ketamine, known for its use in depression treatment and as a recreational drug, has garnered attention for its rapid relief of severe depression. Approved by the Food and Drug Administration (FDA) in 2019, a ketamine nasal spray serves as an adjunct for major depressive disorder. Perry’s case, however, raises questions about the circumstances surrounding additional ketamine intake before his demise, necessitating a thorough examination of its timing and administration.

Matthew Perry’s Struggle with Addiction: Sober at the Time of Death

Matthew Perry had openly shared his battle with addiction, chronicled in his 2022 memoir ‘Friends, Lovers and the Big Terrible Thing.’ Despite his struggles, the autopsy revealed no presence of alcohol, methamphetamine, cocaine, heroin, PCP, or fentanyl in his system at the time of death. Jennifer Aniston, Perry’s ‘F.R.I.E.N.D.S’ co-star, attested to his state of well-being, describing him as “happy, healthy, and not struggling” before his untimely demise.

Investment in Sobriety: Perry’s Determined Journey to Recovery

Perry’s commitment to sobriety was evident in his reported investment of $7-9 million on his journey to recovery, which included undergoing rehabilitation 15 times. This financial and personal investment reflects Perry’s resilience in the face of addiction and his unwavering determination to overcome challenges.

Unanswered Questions Surrounding a Beloved Star’s Passing

In conclusion, the autospy report unveiling the cause of Matthew Perry’s death brings both clarity and complexity to the circumstances surrounding his passing. The unexpected presence of high ketamine levels, combined with contributing factors, paints a nuanced picture. As questions linger about the specifics of additional ketamine intake and the interplay of substances, Perry’s untimely demise serves as a somber reminder of the multifaceted nature of mental health struggles and addiction.

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